■原著論文(査読あり)

  • Hashimoto T1, Horikawa DD1, Saito Y, Kuwahara H, Kozuka-Hata H, Shin-I T, Minakuchi Y, Ohishi K, Motoyama A, Aizu T, Enomoto A, Kondo K, Tanaka S, Hara Y, Koshikawa S, Sagara H, Miura T, Yokobori S, Miyagawa K, Suzuki Y, Kubo T, Oyama M, Kohara Y, Fujiyama A, Arakawa K, Katayama T, *Toyoda A and *Kunieda T (2016) Extremotolerant tardigrade genome and improved radiotolerance of human cultured cells by tardigrade-unique protein. Nature Comm 7, 12808. doi: 10.1038/ncomms12808. 1,authors equally contributed. * corresponding author
  • Ito M1, Saigo T1, Abe W, Kubo T and *Kunieda T1 (2016) Establishment of an isogenic strain of the desiccation-sensitive tardigrade Isohypsibius myrops (Parachela, Eutardigrada) and its life history traits. Zool J Linn Soc 178(4), 863-870. doi: 10.1111/zoj.12449. 1:authors equally contributed. * corresponding author
  • Kondo K, Kubo T and *Kunieda T (2015) Suggested Involvement of PP1/PP2A Activity and De Novo Gene Expression in Anhydrobiotic Survival in a Tardigrade, Hypsibius dujardini, by Chemical Genetic Approach. PLoS ONE 10(12), e0144803. doi: 10.1371/journal.pone.0118272. * corresponding author
  • Tanaka S, Tanaka J, Miwa Y, Horikawa DD, Katayama T, Arakawa K, Toyoda A, Kubo T and *Kunieda T (2015) Novel mitochondria-targeted heat-soluble proteins identified in the anhydrobiotic tardigrade improve osmotic tolerance of human cells. PLoS ONE 10(2), e0118272. doi: 10.1371/journal.pone.0144803. * corresponding author
  • Horikawa DD, Cumbers J, Sakakibara I, Rogoff D, Leuko S, Harnoto R, Arakawa K, Katayama T, Kunieda T, Toyoda A, Fujiyama A and Rothschild LJ (2013) Analysis of DNA repair and protection in the Tardigrade Ramazzottius varieornatus and Hypsibius dujardini after exposure to UVC radiation. PLoS ONE 8(6), e64793. doi: 10.1371/journal.pone.0064793.
  • Yamaguchi A, Tanaka S, Yamaguchi S, Kuwahara H, Takamura C, Imajoh-Ohmi S, Horikawa DD, Toyoda A, Katayama T, Arakawa K, Fujiyama A, Kubo T and *Kunieda T (2012) Two Novel Heat-Soluble Protein Families Abundantly Expressed in an Anhydrobiotic Tardigrade. PLoS ONE 7(8), e44209. * corresponding author
  • Horikawa DD, Yamaguchi A, Sakashita T, Tanaka D, Hamada N, Yukuhiro F, Kuwahara H, Kunieda T, Watanabe M, Nakahara Y, Wada S, Funayama T, Katagiri C, Higashi S, Yokobori S-I, Kuwabara M, Rothschild L J, Okuda T, Hashimoto H, and Kobayashi Y (2012) Tolerance of Anhydrobiotic Eggs of the Tardigrade Ramazzottius varieornatus to Extreme Environments Astrobiology 12(4), 283-289.

  • Takayanagi-Kiya S, Kiya T, Kunieda T and Kubo T (2016) Mblk-1 Transcription Factor Family: Its Roles in Various Animals and Regulation by NOL4 Splice Variants in Mammals. [REVIEW] Int J Mol Sci 18(2), E246. doi: 10.3390/ijms18020246.
  • Hatta-Kobayashi Y, Toyama-Shirai M, Yamanaka T, Takamori M, Wakabayashi Y, Naora Y, Kunieda T, Fukazawa T and Kubo T (2016) Acute phase response in amputated tail stumps and neural tissue-preferential expression in tail bud embryos of the Xenopus neuronal pentraxin I gene. Dev Growth Diff 58(9), 688-701. doi: 10.1111/dgd.12326.
  • Tsujioka H, Kunieda T, Katou Y, Shirahige K and Kubo T (2015) Unique Gene Expression Profile of the Proliferating Xenopus Tadpole Tail Blastema Cells Deciphered by RNA-Sequencing Analysis. PLoS ONE 10(3), e0111655. doi: 10.1371/journal.pone.0111655.
  • Takayanagi-Kiya S, Misawa-Hojo K, Kiya T, Kunieda T and Kubo T (2014) Splicing variants of NOL4 differentially regulate the transcription activity of Mlr1 and Mlr2 in cultured cells. Zoolog Sci 31(11), 735-40. doi: 10.2108/zs140049.
  • Naora Y, Hishida Y, Fukazawa T, Kunieda T and Kubo T (2013) Expression analysis of XPhyH-like during development and tail regeneration in Xenopus tadpoles: possible role of XPhyH-like expressing immune cells in impaired tail regenerative ability. Biochem Biophys Res Commun 431(2), 152-7. doi: 10.1016/j.bbrc.2013.01.005.
  • Ugajin A, Kunieda T and Kubo T (2013) Identification and characterization of an Egr ortholog as a neural immediate early gene in the European honeybee (Apis mellifera L.). FEBS Lett 587(19), 3224-30. doi: 10.1016/j.febslet.2013.08.014.
  • Fujita T, Kozuka-Hata H, Ao-Kondo H, Kunieda T, Oyama M and Kubo T (2013) Proteomic analysis of the royal jelly and characterization of the functions of its derivation glands in the honeybee. J Proteome Res 12(1), 404-11. doi: 10.1021/pr300700e.
  • Kaneko K, Ikeda T, Nagai M, Hori S, Umatani C, Tadano H, Ugajin A, Nakaoka T, Paul RK, Fujiyuki T, Shirai K, Kunieda T, Takeuchi H and Kubo T (2013) Novel middle-type Kenyon cells in the honeybee brain revealed by area-preferential gene expression analysis. PLoS ONE 8(8), e71732. doi: 10.1371/journal.pone.0071732.
  • Ugajin A, Kiya T, Kunieda T, Ono M, Yoshida T and Kubo T (2012) Detection of neural activity in the brains of Japanese honeybee workers during the formation of a “hot defensive bee ball. PLoS ONE 7(3), e32902.
  • Kiya T, Ugajin A, Kunieda T and Kubo T (2012) Identification of kakusei, a nuclear non-coding RNA, as an immediate early gene from the honeybee, and its application for neuroethological study. Int J Mol Sci 13(12), 15496-509. doi: 10.3390/ijms131215496.
  • Fukazawa T, Naora Y, Kunieda T and Kubo T (2009) Suppression of immune response potentiates tadpole tail regeneration during the refractory period. Development 136(14), 2323-2327
  • Horikawa DD, Kunieda T, Abe W, Watanabe M, Nakahara Y, Yukuhiro F, Sakashita T, Hamada,N., Wada S, Funayama T, Katagiri C, Kobayashi Y, Higashi S and Okuda T (2008) Establishment of a rearing system of the extremotolerant tardigrade Ramazzottius variornatus: a new model animal for astrobiology. Astrobiology 8(3), 549-556
  • Kiya T, Kunieda T and Kubo T (2008) Inducible- and constitutive-type transcript variants of kakusei , a novel non-coding immediate early gene, in the honeybee brain. Insect Mol Biol 17(5), 531-536.
  • Iijima R1, Kunieda T1, Yamaguchi S1, Kamigaki H, Fujii-Taira I, Sekimizu K, Kubo T, Natori S and Homma KJ (2008) The extracellular adenosine deaminase growth factor, ADGF/CECR1, plays a role in Xenopus embryogenesis via the adenosine/P1 receptor. J Biol Chem 283(4), 2255-2264. 1:authors equally contributed.
  • Kiya T, Kunieda T and Kubo T (2007) Increased neural activity of a mushroom body neuron subtype in the brains of forager honeybees. PLoS ONE 2(4), e371.
  • Ishino T1, Kunieda T1, Natori S, Sekimizu K and Kubo T (2007) Identification of novel members of the Xenopus Ca2+-dependent lectin family and analysis of their gene expression during tail regeneration and development. J Biochem 141(4), 479-488. 1:authors equally contributed.
  • The Honeybee Genome Sequencing Consortium(申請者の名前はコンソーシアムの一員として論文中に記載)(2006) Insights into social insects from the genome of the honeybee Apis mellifera. Nature 443, 931-949.
  • Kunieda T1, Fujiyuki T1, Kucharski R1, Foret S1, Ament SA.1, Toth AL.1, Ohashi K, Takeuchi H, Kamikouchi A, Kage E, Morioka M, Beye M, Kubo T, Robinson GE and Maleszka R (2006) Carbohydrate metabolism genes and pathways in insects: insights from the honey bee genome. Insect Mol Biol 15(5), 563-576. 1:authors equally contributed.
  • Kunieda T. and Kubo T (2004) In vivo gene transfer into the adult honeybee brain by using electroporation. Biochem Biophys Res Commun 318(1), 25-31.
  • Park J-M, Kunieda T and Kubo T (2003) The activity of Mblk-1, a mushroom body-selective transcription factor from the honeybee, is modulated by the Ras/MAPK pathway. J Biol Chem 278, 18689-18694.
  • Kunieda T1, Park J-M1, Takeuchi H. and Kubo T (2003) Identification and characterization of Mlr1,2: two mouse homologues of Mblk-1, a transcription factor from the honeybee brain. FEBS Lett 535, 61-65. 1:authors equally contributed.
  • Ishino T, Shirai M, Kunieda T, Sekimizu K, Natori S and Kubo T (2003) Identification of genes induced in regenerating Xenopus tadpole tails by using the differential display method. Dev Dyn 226, 317-325.
  • Park J-M1, Kunieda T1, Takeuchi H and Kubo T (2002) DNA-binding properties of Mblk-1, a putative transcription factor from the honeybee. Biochem Biophys Res Commun 291, 23-28. 1:authors equally contributed.
  • Takeuchi H, Kage E, Sawata M, Kamikouchi A, Ohashi K, Ohara M, Fujiyuki T, Kunieda T, Sekimizu K, Natori S and Kubo T (2001) Identification of a novel gene, Mblk-1, that encodes a putative transcription factor expressed preferentially in the large-type Kenyon cells of the honeybee brain. Insect Mol Biol 10, 487-494.
  • Kunieda T, Kurata S and Natori S (1997) Regeneration of Sarcophaga imaginal discs in vitro: implication of 20-hydroxyecdysone. Dev Biol 183, 86-94.

■書籍

  • 「極限環境生命」(コロナ社)伊藤政博, 鳴海一成, 佐藤孝子, 中村聡, 東端啓貴, 國枝武和, 為我井秀行, 道久則之, 伊藤隆(分担執筆)2014年10月

■和文総説

  • 國枝武和 (2012) 緩歩動物クマムシの乾眠能力と極限環境耐性 生物科学 63(4), 205-213.
  • 深澤太郎,直良悠子,國枝武和,久保健雄 (2011) 『免疫抑制による“再生不応期”のアフリカツメガエル幼生尾の再生能の人為的活性化:脊椎動物の器官再生能の有無を決定する要因を探る』 Special Review、 細胞工学 30(4), 418-423.
  • 堀川大樹、國枝武和 (2007) 高い放射線耐性をもつ動物「クマムシ」東京大学アイソトープ総合センターニュース 38(3), 2-4.
  • 國枝武和 (2007) 第一回クマムシ研究会 科学 77(4), 338-339.
  • 國枝武和、藤幸知子、久保健雄 (2007) 社会性昆虫ミツバチのゲノムが語るもの 生物の科学・遺伝61(2), 4-7.
  • 國枝武和 (2006) 動物の乾燥耐性を支える分子基盤を探る 化学と生物 44(11), 732-734.
  • 國枝武和、久保健雄 (2005) ミツバチ脳の高次中枢(キノコ体)選択的に発現する新規転写因子Mblk-1のリン酸化による活性制御 日本応用酵素協会誌 40, 25-32.
  • 竹内秀明、國枝武和、徳廣(澤田)美由紀、朴正敏、藤幸知子、久保健雄 (2004) ミツバチをモデル生物とした分子行動生物学 蛋白質・核酸・酵素 49(16), 2542-2548.

■招待講演

  • 國枝武和 『クマムシの耐性の秘密を探る』 第37回土壌動物学会年会、川越、2014年5月
  • 國枝武和 『極限環境耐性動物クマムシのゲノム解析と機能プロテオミクス』 沖縄知的クラスター形成シンポジュウム、那覇、2011年1月
  • 國枝武和 『極限環境に耐える動物:クマムシの仕組みを探る』 第8回極限環境微生物学会年会、福岡、2007年11月