Department of Biological Sciences Graduate School of Science The University of Tokyo
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Laboratory of Biological Signaling


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Yoshitaka OKA (Professor)
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Min Kun PARK (Associate Professor)
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Selected publications

Saito, T., Nakane, R., Akazome, Y., Abe, H., and Oka, Y. (2010) Electrophysiological analysis of the inhibitory effects of FMRFamide-like peptides on the pacemaker activity of gonadotropin-releasing hormone neurons. TS&RN: equal contribution, Journal of Neurophysiology 104: 3518-3529.

Mitani, Y., Kanda, S., Akazome, Y., Zempo, B., and Oka, Y. (2010) Hypothalamic kiss1 but not kiss2 neurons are involved in estrogen feedback in medaka (Oryzias latipes). YM&SK: equal contribution, Endocrinology 151: 1751–1759.

Kanda, S., Nishikawa, K., Karigo, T., Okubo, K., Isomae, S, Abe, H., Kobayashi, D., and Oka, Y. (2010) Regular pacemaker activity characterizes gonadotropin-releasing hormone 2 neurons recorded from green fluorescent protein-transgenic medaka. SK&KN: equal contribution, Endocrinology 151: 695-701.

Kanda, S., Akazome, Y., Yamamoto, N., Yamada, S., Tsukamura, H., Maeda, K., and Oka, Y. (2008) Identification of KiSS-1 product kisspeptin and steroid-sensitive sexually-dimorphic kisspeptin neurons in medaka (Oryzias latipes). Endocrinology 149: 2467-2476.

Abe, H. and Oka, Y. (2007) Neuromodulatory functions of terminal nerve-GnRH neurons. Fish Physiology Vol. 25, Sensory Systems Neuroscience. Elsevier, San Diego, pp. 455-503.



Endo D., Murakami S., Akazome Y. and Park MK. (2007) Sex difference in Ad4BP/SF-1 mRNA expression in the chick-embryo brain before gonadal sexual differentiation. Zool. Sci. 24: 877-882.

Ikemoto T. and Park MK. (2007) Comparative analysis of the pituitary and ovarian GnRH systems in the leopard gecko: signaling crosstalk between multiple receptor subtypes in ovarian follicles. J Mol Endocrinol. 38: 289-304.

Enomoto M., Utsumi M. and Park MK. (2006) Gonadotropin-releasing hormone induces actin cytoskeleton remodeling and affects cell migration in a cell-type-specific manner in TSU-Pr1 and DU145 cells. Endocrinology 147: 530-542.

Ikemoto T. and Park MK. (2005) Identification and molecular characterisation of three GnRH ligands and five GnRH receptors in the spotted green pufferfish. Mol Cell Endocrinol. 242: 67-79.

Enomoto M. and Park MK. (2004) GnRH as a cell proliferation regulator; mechanism of the action and evolutionary implications. Zool. Sci. 21: 1005-1013.


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Department of Biological Science, Graduate School of Science,The University of Tokyo